{"id":18682,"date":"2026-06-30T19:41:01","date_gmt":"2026-06-30T17:41:01","guid":{"rendered":"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/huntingtons-disease\/"},"modified":"2026-07-09T21:12:37","modified_gmt":"2026-07-09T19:12:37","slug":"huntingtons-disease","status":"publish","type":"page","link":"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/huntingtons-disease\/","title":{"rendered":"Huntington&#8217;s disease"},"content":{"rendered":"<div class=\"hero-header__outer-container\">\n\n\t<div class=\"hero hero--styled color-theme--denim-blue hero--no-image hero--normal-spacing\">\n\t\t\t\t\t\t<div class=\"hero__bg\">\n\t\t\t<div id=\"particles-js\" class=\"hero__constellation hero__constellation--center\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"hero__inner hero__inner--center\">\n\t\t\t<div class=\"hero__content hero__content--center hero__content--no-image\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-mt-1 u-my-2\"><h1 class=\"hero__title hero__title--standard\" data-ptc-fitty=\"\">Huntington&#8217;s Disease (HD)<\/h1><\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"hero__subtitle\">Progressive brain disorder that causes uncontrolled movements and cognitive loss<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"hero__breadcrumbs\"><nav\n\tclass=\"breadcrumbs breadcrumbs--deep\"\n\taria-label=\"Breadcrumb\"\n>\n\t<ol class=\"breadcrumbs__list\" itemscope itemtype=\"https:\/\/schema.org\/BreadcrumbList\">\n\t\t\t\t\t\t\t\t\t<li class=\"breadcrumbs__crumb breadcrumbs__crumb--light\" itemscope itemprop=\"itemListElement\" itemtype=\"https:\/\/schema.org\/ListItem\">\n\t\t\t\t\t\t\t\t\t\t\t<a class=\"breadcrumbs__link breadcrumbs__link--home breadcrumbs__link--light\" itemprop=\"item\" href=\"https:\/\/panel.ptcbio.com\/es\/\">\n\t\t\t\t\t\t\t<span class=\"sr-only\" itemprop=\"name\">Homepage<\/span>\n\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t<meta itemprop=\"position\" content=\"1\" \/>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"breadcrumbs__crumb breadcrumbs__crumb--light\" itemscope itemprop=\"itemListElement\" itemtype=\"https:\/\/schema.org\/ListItem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\tclass=\"breadcrumbs__link\" itemprop=\"item\"\n\t\t\t\t\t\t\t\thref=\"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span itemprop=\"name\">Therapeutic Areas<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<meta itemprop=\"position\" content=\"2\" \/>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"breadcrumbs__crumb breadcrumbs__crumb--light\" itemscope itemprop=\"itemListElement\" itemtype=\"https:\/\/schema.org\/ListItem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span\n\t\t\t\t\t\t\t\tclass=\"breadcrumbs__current\" itemprop=\"item\"\n\t\t\t\t\t\t\t\taria-current=\"page\"\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t<span itemprop=\"name\">Huntington&#8217;s disease<\/span>\n\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<meta itemprop=\"position\" content=\"3\" \/>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ol>\n<\/nav>\n<\/div>\n\t<\/div>\n\n\n\n<h4 id=\"h-what-is-huntington-s-disease\" class=\"wp-block-heading\">What is Huntington&#8217;s Disease?<\/h4>\n\n\n\n<figure class=\"wp-block-image alignright size-full is-style-lightbox\"><img decoding=\"async\" src=\"https:\/\/www.ptcbio.com\/wp-content\/uploads\/sites\/2\/2024\/06\/HD-Symptoms.jpg\" alt=\"Huntington's Disease Symptoms\" class=\"wp-image-15587\"\/><button class=\"modal-toggle\" type=\"button\" data-bs-toggle=\"modal\" data-bs-target=\"#mg-image-modal\" aria-label=\"View image in lightbox\"><img fetchpriority=\"high\" decoding=\"async\" width=\"630\" height=\"613\" src=\"https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-Symptoms.jpg\" class=\"attachment-full size-full\" alt=\"\" hidden=\"\" loading=\"eager\" srcset=\"https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-Symptoms.jpg 630w, https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-Symptoms-300x292.jpg 300w, https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-Symptoms-400x389.jpg 400w\" sizes=\"(max-width: 630px) 100vw, 630px\" \/><\/button><\/figure>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">Huntington\u2019s disease is a rare, hereditary, genetic disorder of the central nervous system.<sup>1<\/sup>&nbsp;It is caused by a defective gene. This gene produces a protein, called huntingtin, which is involved in the functioning of the nerve cells in the brain (neurons). When the gene is defective, it produces an abnormal (or mutated) huntingtin protein that is toxic and causes neuron damage and neuron death.<sup>2<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">Huntington\u2019s disease usually presents in people who are in their 30s or 40s.&nbsp;Symptoms can present earlier in life, and this is called Juvenile Huntington\u2019s disease.<sup>2,3<\/sup>&nbsp;There are also cases of infantile Huntington\u2019s disease, when symptoms develop in children who are younger than 10 years old.<sup>2<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">While symptoms vary from person to person, the disease primarily affects the brain and results in abnormal movements, difficulties with speech, swallowing and walking, as well as a number of other symptoms including:<sup>4,5<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\"><strong>Behavioral symptoms:<\/strong>&nbsp;Frequently present in the early stage of Huntington\u2019s disease, these symptoms include irritability, agitation, depression, euphoria, apathy, anxiety, delusions, and hallucinations.<sup>4,5,6<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\"><strong>Cognitive symptoms:<\/strong>&nbsp;Usually develop gradually, at least 15 years before motor symptoms, and include poor attention, difficulty planning and thinking, memory loss, and dementia.<sup>7,8,9<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\"><strong>Motor symptoms:<\/strong>&nbsp;Involuntary, unwanted movements that usually start in the extremities, such as the fingers and toes, before spreading to other muscles. This leads to difficulties standing and walking, clumsiness, rigidity, trouble holding objects, and speech and swallowing difficulties.<sup>4,5<\/sup><\/p>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\"><\/p>\n\n\n\n<h4 id=\"h-how-common-is-huntington-s-disease\" class=\"wp-block-heading\">How Common is Huntington&#8217;s Disease?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">Men and women are equally likely to inherit the defective gene and develop Huntington\u2019s disease.<sup>10<\/sup> While Huntington\u2019s disease affects approximately 135,000 globally, the prevalence varies greatly between countries.1<sup>1,12,13<\/sup> In North America, North-Western Europe, and Australia prevalence ranges from almost 6 cases per 100,000 people to almost 14 cases.<sup>14<\/sup> Prevalence in Asia is much lower, at less than 1 case per 100,000 people.<sup>11<\/sup><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized is-style-lightbox\"><img decoding=\"async\" src=\"https:\/\/www.ptcbio.com\/wp-content\/uploads\/sites\/2\/2024\/06\/HD.jpg\" alt=\"HD affects approximately 135,000 people globally, and men and women are equally likely to inherit the defective HD gene and develop HD\" class=\"wp-image-15606\" style=\"width:482px;height:auto\"\/><button class=\"modal-toggle\" type=\"button\" data-bs-toggle=\"modal\" data-bs-target=\"#mg-image-modal\" aria-label=\"View image in lightbox\"><img decoding=\"async\" width=\"702\" height=\"348\" src=\"https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD.jpg\" class=\"attachment-full size-full\" alt=\"\" hidden=\"\" loading=\"eager\" srcset=\"https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD.jpg 702w, https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-300x149.jpg 300w, https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/HD-400x198.jpg 400w\" sizes=\"(max-width: 702px) 100vw, 702px\" \/><\/button><\/figure>\n\n\n\n<h4 id=\"h-is-it-treatable\" class=\"wp-block-heading\">Is it Treatable?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">While there are therapies approved for specific disease symptoms, currently, there is no cure for Huntington\u2019s disease and there are no approved drugs that delay the onset or slow disease progression.<\/p>\n\n\n\n<h4 id=\"h-how-is-ptc-working-to-treat-huntington-s-disease\" class=\"wp-block-heading\">How is PTC Working to Treat Huntington&#8217;s Disease?<\/h4>\n\n\n\n<p class=\"wp-block-paragraph core-block core-paragraph\">PTC is developing a potential treatment for Huntington\u2019s disease, based on our <a href=\"https:\/\/www.ptcbio.com\/our-science\/splicing\/\">splicing platform technology<\/a>. PTC518, a small molecule that can be taken orally, reduces the production of the mutated huntingtin protein that leads to injury and death of the neuron, which results in disease progression.<\/p>\n\n\n\n<div  class=\"quote-block quote-block--image color-theme--light-blue\">\n\n\t\t\t<img decoding=\"async\" src=\"https:\/\/panel.ptcbio.com\/es\/wp-content\/uploads\/sites\/20\/2026\/06\/Brian-Beers-scaled-1-342x429.jpg\" class=\"quote-block__image\" alt=\"\"\/>\n\t\n\t<div class=\"quote-block__content\">\n\t\t<blockquote class=\"quote-block__text color-theme-border--light-blue\">\n\t\t\t<div class=\"quote-block__heading heading--4\">\n\t\t\t\tTo be involved in such a promising development program with many eyes across the world on us, motivates me and the team to work together and passionately to move this program forward.\t\t\t<\/div>\n\t\t<\/blockquote>\n\n\t\t\t\t\t<cite class=\"quote-block__author quote-block__author--name\">\n\t\t\t\tBrian Beers\t\t\t<\/cite>\n\t\t\n\t\t\t\t\t<cite class=\"quote-block__author quote-block__author--title\">\n\t\t\t\tGlobal Huntington\u2019s disease Project Leader, PTC\t\t\t<\/cite>\n\t\t\t<\/div>\n\n<\/div>\n\n\n\n\n<div  class=\"references-block color-theme--purple-steel\">\n\t<div class=\"references-block__wrapper\">\n\n\t\t\t\t\t<div class=\"references-block__title heading--6\">\n\t\t\t\tReferences\t\t\t<\/div>\n\t\t\n\t\t<div class=\"references-block__content wysiwyg wysiwyg--pure\">\n\t\t\t<p>[1] World Health Organization, 2020.\u00a0<em>8A01.10 Huntington disease.<\/em>\u00a0Available at:\u00a0<a href=\"https:\/\/icd.who.int\/browse11\/l-m\/en#\/http:\/\/id.who.int\/icd\/entity\/2132180242\">https:\/\/icd.who.int\/browse11\/l-m\/en#\/http:\/\/id.who.int\/icd\/entity\/2132180242<\/a>\u00a0Accessed\u00a0October\u00a02021.<\/p>\n<p>[2] Gatto EM, Gonz\u00e1lez Rojas N, Persi G, et al. Clin Parkinsonism Rel Disord 2020;3:100056.<\/p>\n<p>[3] Tabrizi SJ, Flower MD, Ross CA, et al. Nat Rev Neurol 2020;16(10):529\u2013546.<\/p>\n<p>[4] Roos RAC. Orphanet J Rare Dis 2010;5:40.<\/p>\n<p>[5] Kirkwood SC, Su JL, Conneally P, et al. Arch Neurol 2001;58(2):273\u2013278.<\/p>\n<p>[6] Paulsen JS , Ready RE, Hamilton JM, et al. J Neurol Neurosurg Psychiatry 2001;71:310\u2013314.<\/p>\n<p>[7] Paulsen JS. Curr Neurol Neurosci Rep 2011;11(5):474\u2013483.<\/p>\n<p>[8] Stout JC, Paulsen JS, Queller S, et al. Neuropsychology 2011;25(1):1\u201314.<\/p>\n<p>[9] Papoutsi M, Labuschagne I, Tabrizi S, et al. Movement Disorders 2014;29(5):673\u2013683.<\/p>\n<p>[10] European Huntington\u2019s Disease Network, 2016. About Huntington\u2019s Disease. Available at: http:\/\/www.ehdn.org\/about-hd\/. Accessed October 2021.<\/p>\n<p>[11] Fisher ER, Hayden MR. Multisource ascertainment of Huntington disease in Canada: prevalence and population at risk. Mov Disord. 2014;29(1):105-114.<\/p>\n<p>[12] Overview of Huntington&#8217;s disease. (n.d.). Retrieved April 01, 2021, from https:\/\/hdsa.org\/what-is-hd\/overview-of-huntingtons-disease\/#:~:text=Huntington&#8217;s%20disease%20(Huntington\u2019s disease)%20is%20a,years%20and%20has%20no%20cure<\/p>\n<p>[13] Rawlins MD, Wexler NS, Wexler AR, et al. Neuroepidemiology 2016;46:144\u2013153.<\/p>\n<p>[14] Baig SS, Strong M, Quarrell OW. Neurodegener Dis Manag 2016;6(4):331\u2013343.<\/p>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<div  class=\"text-block text-block--standard color-theme--sky-blue-partial\">\n\t\t<div class=\"text-block__wrapper\" >\n\n\t\t\n\t\t\t\t\t<h2 class=\"text-block__heading\">\n\t\t\t\t<span class=\"heading--2\"  data-ptc-fitty=\"\">Do you have questions?<\/span>\n\t\t\t<\/h2>\n\t\t\n\t\t<div class=\"text-block__content wysiwyg--decoration wysiwyg--color\">\n\t\t\t<p><span class=\"NormalTextRun SCXP77754502 BCX0\">Please reach out if you would like to speak with\u00a0<\/span><span class=\"NormalTextRun SCXP77754502 BCX0\">us.<\/span><\/p>\n\t\t<\/div>\n\n\t\t\n\t\t\t<div class=\"dual-cta__ctas dual-cta__ctas--same dual-cta__ctas--center\">\n\n\t\t\t\t\t<a href=\"mailto:PatientInfo@ptcbio.com\" target=\"\" class=\"dual-cta__button btn btn--primary\">Patients and Families<\/a>\n\t\t\n\t\t\t\t\t<a href=\"mailto:MedInfo@ptcbio.com\" target=\"\" class=\"dual-cta__button btn btn--primary\">Healthcare Professionals<\/a>\n\t\t\n\t\t\n\t<\/div>\n\n\t<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>What is Huntington&#8217;s Disease? Huntington\u2019s disease is a rare, hereditary, genetic disorder of the central nervous system.1&nbsp;It is caused by a defective gene. This gene produces a protein, called huntingtin, which is involved in the functioning of the nerve cells in the brain (neurons). When the gene is defective, it produces an abnormal (or mutated)&hellip;<\/p>\n","protected":false},"author":14,"featured_media":0,"parent":18644,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-18682","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.9 (Yoast SEO v27.9) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Huntington&#039;s disease - PTC Therapeutics (Spain)<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/huntingtons-disease\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Huntington&#039;s disease\" \/>\n<meta property=\"og:description\" content=\"What is Huntington&#8217;s Disease? Huntington\u2019s disease is a rare, hereditary, genetic disorder of the central nervous system.1&nbsp;It is caused by a defective gene. This gene produces a protein, called huntingtin, which is involved in the functioning of the nerve cells in the brain (neurons). When the gene is defective, it produces an abnormal (or mutated)&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/huntingtons-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"PTC Therapeutics (Spain)\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-09T19:12:37+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/\",\"url\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/\",\"name\":\"Huntington's disease - PTC Therapeutics (Spain)\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ptcbio.com\\\/wp-content\\\/uploads\\\/sites\\\/2\\\/2024\\\/06\\\/HD-Symptoms.jpg\",\"datePublished\":\"2026-06-30T17:41:01+00:00\",\"dateModified\":\"2026-07-09T19:12:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.ptcbio.com\\\/wp-content\\\/uploads\\\/sites\\\/2\\\/2024\\\/06\\\/HD-Symptoms.jpg\",\"contentUrl\":\"https:\\\/\\\/www.ptcbio.com\\\/wp-content\\\/uploads\\\/sites\\\/2\\\/2024\\\/06\\\/HD-Symptoms.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/huntingtons-disease\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Therapeutic Areas\",\"item\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/therapeutic-areas\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Huntington&#8217;s disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#website\",\"url\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/\",\"name\":\"PTC Therapeutics Espa\u00f1a\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#organization\",\"name\":\"PTC Therapeutics Espa\u00f1a\",\"url\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/wp-content\\\/uploads\\\/sites\\\/20\\\/2026\\\/04\\\/ptcLogo.png\",\"contentUrl\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/wp-content\\\/uploads\\\/sites\\\/20\\\/2026\\\/04\\\/ptcLogo.png\",\"width\":542,\"height\":542,\"caption\":\"PTC Therapeutics Espa\u00f1a\"},\"image\":{\"@id\":\"https:\\\/\\\/panel.ptcbio.com\\\/es\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Huntington's disease - PTC Therapeutics (Spain)","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/panel.ptcbio.com\/es\/therapeutic-areas\/huntingtons-disease\/","og_locale":"es_ES","og_type":"article","og_title":"Huntington's disease","og_description":"What is Huntington&#8217;s Disease? Huntington\u2019s disease is a rare, hereditary, genetic disorder of the central nervous system.1&nbsp;It is caused by a defective gene. This gene produces a protein, called huntingtin, which is involved in the functioning of the nerve cells in the brain (neurons). 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